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Avapritinib

Details of the Drug
Generic Name:
Avapritinib
Drug Type:
Kinase inhibitor
How the Drug is Given:

By mouth

Names:
Ayvakit™
Avapritinib

Indications and Usage

Ayvakit™ is indicated for the treatment of adult patients with Advanced Systemic Mastocytosis (AdvSM). AdvSM includes patients with aggressive systemic mastocytosis (ASM), systemic mastocytosis with an associated hematological neoplasm (SMAHN), and mast cell leukemia (MCL).  

Limitations of Use: AYVAKIT is not recommended for the treatment of patients with AdvSM with platelet counts of less than 50 X 109 /L.
 

Side effects needing medical attention

The most common adverse reactions for AdvSM are: edema, diarrhea, nausea, and fatigue/asthenia.

For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.